Aracea Therapeutics

How brown fat improves metabolism

How brown fat improves metabolism At a Glance Researchers gained key insights into brown fat’s effects on the body’s metabolism. The findings reveal targets for developing new treatments for obesity and diabetes. Metabolism involves the chemical reactions that break down the food we eat into sugars, fats, and amino acids. We use these compounds for … Read more

Signals from skin cells control fat cell specialization

When cells change to a more specialized type, we call this process cellular differentiation. Scientists have revealed that protein secretions by skin cells known as keratinocytes control the differentiation of subsurface skin fat cells. This discovery could potentially help to treat obesity. Associate Professor Takehiko Ueyama and Professor Naoaki Saito at the Biosignal Research Center … Read more

What made humans ‘The Fat Primate’?

Changes in DNA packaging curbed our body’s ability to turn ‘bad’ fat into ‘good’ fat Blame junk food or a lack of exercise. But long before the modern obesity epidemic, evolution made us fat too. “We’re the fat primates,” said Devi Swain-Lenz, a postdoctoral associate in biology at Duke University. The fact that humans are … Read more

Gut hormone and brown fat interact to tell the brain it’s time to stop eating

Researchers from Germany and Finland have shown that so-called “brown fat” interacts with the gut hormone secretin in mice to relay nutritional signals about fullness to the brain during a meal. The study, appearing November 15 in the journal Cell, bolsters our understanding of a long-suspected role of brown adipose tissue (BAT) — a type … Read more

Obesity: We inherit the dangerous fat from Dad ‒ and the good fat from Mom

A team of researchers, led by Professor Jan-Wilhelm Kornfeld from the Department of Biochemistry and Molecular Biology, University of Southern Denmark, Elena Schmidt from the Max Planck Institute for Metabolism Research, Cologne, Germany and Martin Bilban from the Medial University, Vienna, Austria, have made a groundbreaking discovery in obesity research. The team has discovered a … Read more