Aracea Therapeutics

Giving brown fat a green light

Fat-like molecules induced by cold help to turn-on calorie-burning fat and improve metabolism Activated by cold, the small amounts of brown fat scattered around your body can burn calories to warm you up. They also can help to lower insulin resistance and other conditions implicated in type 2 diabetes and obesity. Since the discovery in … Read more

Scientists discover drug that increases ‘good’ fat mass and function

Anti-cancer drug prevented weight gain and caused mice to burn more calories thanks to higher levels of metabolism-boosting brown fat Scientists at the Gladstone Institutes identified an FDA-approved drug that can create the elusive and beneficial brown fat. Mice treated with the drug had more brown fat, faster metabolisms, and lower body weight gain, even … Read more

Brown adipose tissue secretes factors that activate fat and carbohydrate metabolism

Brown adipose tissue — main organ generating heat in the body- is also an endocrine organ that secretes signaling factors that activate the fat and carbohydrates metabolism. Key Points The activity of brown adipose tissue (BAT) is associated with protection against obesity and associated metabolic alterations such as insulin resistance Experimental evidence indicates that BAT … Read more

Researchers identify calorie-burning pathway in fat cells

Findings show potential for obesity treatment Investigators at Dana-Farber Cancer Institute in collaboration with scientists at the University of California, Berkeley, have identified a natural molecular pathway that enables cells to burn off calories as heat rather than store them as fat. This raises the possibility of a new approach to treating and preventing obesity, … Read more

Stress could help activate brown fat

Mild stress stimulates the activity and heat production by brown fat associated with raised cortisol, according to a study published in Experimental Physiology. Brown adipose tissue (BAT), also known as brown fat, is one of two types of fat found in humans and other mammals. Initially only attributed to babies and hibernating mammals, it was … Read more

A pill to shed fat?

Harvard stem cell researchers say they finally can turn ‘bad’ fat into ‘good’ Harvard Stem Cell Institute (HSCI) researchers have taken what they describe as “the first step toward a pill that can replace the treadmill” for the control of obesity, though that shift, of course, would not provide all of the many benefits of … Read more