Aracea Therapeutics

Obesity: We inherit the dangerous fat from Dad ‒ and the good fat from Mom

A team of researchers, led by Professor Jan-Wilhelm Kornfeld from the Department of Biochemistry and Molecular Biology, University of Southern Denmark, Elena Schmidt from the Max Planck Institute for Metabolism Research, Cologne, Germany and Martin Bilban from the Medial University, Vienna, Austria, have made a groundbreaking discovery in obesity research. The team has discovered a … Read more

Potential target for developing obesity and diabetes treatment identified

A newly published study by researchers from the University of Colorado School of Medicine has identified a potential therapeutic target for treating obesity and diabetes. The scientists studied the biological function of an epigenetic modifier known as histone deacetylase 11 (HDAC11), and determined that deleting it in mice stimulates the formation of brown adipose tissue. … Read more

New light shed on relationship between calorie-burning fat and muscle function

Researchers open the door to potential new therapies for certain metabolic and muscular diseases Abundant in human babies and small mammals, brown adipose tissue (BAT), or brown fat, was only recently discovered in human adults, and its role remains unclear. Known to play an integral part in generating body heat and burning stored energy, its … Read more

Skin patch dissolves ‘love handles’ in mice

Microneedle skin patch that delivers fat-shrinking drug locally could be used to treat obesity and diabetes Researchers have devised a medicated skin patch that can turn energy-storing white fat into energy-burning brown fat locally while raising the body’s overall metabolism. The patch could be used to burn off pockets of unwanted fat such as “love … Read more

Giving brown fat a green light

Fat-like molecules induced by cold help to turn-on calorie-burning fat and improve metabolism Activated by cold, the small amounts of brown fat scattered around your body can burn calories to warm you up. They also can help to lower insulin resistance and other conditions implicated in type 2 diabetes and obesity. Since the discovery in … Read more