Anti-cancer drug prevented weight gain and caused mice to burn more calories thanks to higher levels of metabolism-boosting brown fat Scientists at the Gladstone Institutes identified an FDA-approved drug that can create the elusive and beneficial brown fat. Mice treated with the drug had more brown fat, faster metabolisms, and lower body weight gain, even … Read more
Brown adipose tissue — main organ generating heat in the body- is also an endocrine organ that secretes signaling factors that activate the fat and carbohydrates metabolism. Key Points The activity of brown adipose tissue (BAT) is associated with protection against obesity and associated metabolic alterations such as insulin resistance Experimental evidence indicates that BAT … Read more
Findings show potential for obesity treatment Investigators at Dana-Farber Cancer Institute in collaboration with scientists at the University of California, Berkeley, have identified a natural molecular pathway that enables cells to burn off calories as heat rather than store them as fat. This raises the possibility of a new approach to treating and preventing obesity, … Read more
DelveInsight’s Metabolic disorders based Gene Therapy Reports Metabolic disorders are collectively common, frequently severe and in many instances difficult or impossible to treat. Accordingly, there is a compelling need to explore novel therapeutic modalities, including gene therapy, and examine multiple phenotypes where the risks of experimental therapy are outweighed by potential benefits to trial participants. … Read more
Harvard stem cell researchers say they finally can turn ‘bad’ fat into ‘good’ Harvard Stem Cell Institute (HSCI) researchers have taken what they describe as “the first step toward a pill that can replace the treadmill” for the control of obesity, though that shift, of course, would not provide all of the many benefits of … Read more
Is brown fat ready for therapeutic prime time? Nearly 500 million adults worldwide are obese—close to 10 percent of men and 14 percent of women, an incidence twice as high as in 1980, according to the World Health Organization. Obesity, defined as a body mass index of 30 or greater, has been linked with higher … Read more